OAS1, 2'-5'-oligoadenylate synthetase 1, 4938

N. diseases: 72; N. variants: 11
Disease: Infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714514
Disease: Infection
Infection 		0.040 GeneticVariation group LHGDN Single nucleotide polymorphisms in genes for 2'-5'-oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection. 16235172 2005
CUI: C3714514
Disease: Infection
Infection 		0.040 GeneticVariation group LHGDN Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene. 15732009 2005
CUI: C3714514
Disease: Infection
Infection 		0.040 GeneticVariation group LHGDN Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: roles of MxA, OAS-1 and PKR. 12944978 2003
CUI: C3714514
Disease: Infection
Infection 		0.040 Biomarker group LHGDN 2'-5' Oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells. 11980899 2002