OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Alcohol abuse ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.510 Biomarker disease PSYGENET The association between the OPRM1 A118G (Asn40Asp, rs1799971) polymorphism and alcohol use disorders and alcohol consumption was analyzed using three different population-based samples: (a) a Finnish cohort study, Health 2000, with 503 participants having a DSM-IV diagnosis for alcohol dependence and/or alcohol abuse and 506 age- and sex-matched controls; (b) a Finnish cohort study, FINRISK (n = 2360) and (c) the Helsinki Birth Cohort Study (n = 1384). 23729673 2014
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.510 GeneticVariation disease BEFREE The association between the OPRM1 A118G (rs1799971" genes_norm="4988">Asn40Asp, rs1799971) polymorphism and alcohol use disorders and alcohol consumption was analyzed using three different population-based samples: (a) a Finnish cohort study, Health 2000, with 503 participants having a DSM-IV diagnosis for alcohol dependence and/or alcohol abuse and 506 age- and sex-matched controls; (b) a Finnish cohort study, FINRISK (n = 2360) and (c) the Helsinki Birth Cohort Study (n = 1384). 23729673 2014
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.510 Biomarker disease PSYGENET Variation at the human mu-opioid receptor has been associated with alcohol abuse. 20153935 2010
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.510 Biomarker disease CTD_human Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. 12815747 2003