Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The ITM and control ICG-loaded PEG-PLGA micelles (IM) were injected into the right hind footpads in the SLN metastasis model, and the migration and retention of micelles were recorded under near-infrared fluorescence.
|
31695771 |
2019 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Thus, replacing Chol-siRNA with Chol-DsiRNA may significantly increase the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) and possibly other PEGylated polycationic polymers in primary tumors and metastases after i.v. administration.
|
29601972 |
2018 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The results above indicatd that the CRD-PEG-T7-plasmid DNA complex may prove to be a promising gene delivery system targeting bone-metastatic tumor.
|
30464450 |
2018 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Confirmed by long-term survival curve study, CuS@mSiO<sub>2</sub>-PEG NPs significantly reduced the metastasis of cancer cells and improved the survival rates of metastasis in a mouse model.
|
29317819 |
2018 |
Neoplasm Metastasis
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Combination of PEG-GM-CSF treatment with radiation also did not increase tumor cell migration.
|
29536224 |
2018 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Glycodelin expression correlated between primary tumor and distant metastases within the same patients.
|
30518088 |
2018 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
It has been demonstrated that the PEG-CS is a safe and efficient vector for siRNA delivery, and it can effectively reduce tumor growth and prevent metastasis.
|
27729789 |
2017 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In animal tests, more scFv<sub>CD</sub><sub>44v6</sub> -PEG-polyethylenimine/ASO-magnetic iron oxide NP/Gem accumulated at the tumor site than non-targeted NPs and induced a potent inhibition of tumor proliferation and metastasis.
|
28444967 |
2017 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The results showed that paclitaxel nanoparticle carried by PDLLA-PEG-PDLLA gel illustrated good liver metastatic cancer suppression efficacy.
|
31271140 |
2017 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
PEG-Poly(amino acid)s/MicroRNA Complex Nanoparticles Effectively Arrest the Growth and Metastasis of Colorectal Cancer.
|
29337490 |
2016 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Glycodelin was detected in the sera of patients, and the levels correlated with recurrence and metastatic disease.
|
25901080 |
2015 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
We demonstrated that appreciable tumor shrinkage and metastasis inhibition could be achieved with a simple and low toxic chemical carrier - a PEI-PEG copolymer.
|
25880666 |
2015 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Moreover, the patients with glycodelin-positive tumours had an increased risk for distant metastases (P = 0.001) and in multivariate analysis glycodelin expression was an independent predictor of metastasis (hazard ratio (HR) = 2.22, 95% confidence interval (95% CI) = 1.22-4.03, P = 0.009) in familial non-BRCA1/2 breast cancer.
|
20676758 |
2011 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Reduction by glycodelin transfection of carcinoma cell proliferation and expression of MUC1 and Bcl-XL is significant because these genes are often overexpressed in human cancers--MUC1 is linked to invasive growth and metastases, and both confer resistance to chemotherapy.
|
16325596 |
2005 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Results demonstrate that invasive breast carcinomas without metastases are more likely to express glycodelin.
|
15706409 |
2005 |