ANGPTL4, angiopoietin like 4, 51129

N. diseases: 198; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis
0.320 Biomarker disease BEFREE In this study, we aimed to investigate the role of ANGPTL-4 in pathogenesis of hepatic steatosis by determining its levels in patients with fatty liver disease. 29908922 2018
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis
0.320 Biomarker disease CTD_human The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure. 28842503 2017
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis
0.320 Biomarker disease BEFREE We found that mice lacking ANGPTL4 (Angptl4(-/-)) had reductions in dexamethasone-induced hypertriglyceridemia and hepatic steatosis, suggesting that ANGPTL4 is required for this flux. 19628874 2009