DisGeNET - a database of gene-disease associations

PDGFRA, platelet derived growth factor receptor alpha, 5156

N. diseases: 452; N. variants: 44

Disease: Cleft palate, isolated ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C1837218
Disease:	Cleft palate, isolated

Cleft palate, isolated

0.310

Biomarker

disease

BEFREE

This is the first study providing evidence supporting a role of PDGFRa in human CP.

22473090

2012

CUI:	C1837218
Disease:	Cleft palate, isolated

Cleft palate, isolated

0.310

Biomarker

disease

CTD_human

MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis.

18264099

2008