Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 Biomarker disease BEFREE Notably, reduced expression of miRNA‑21 replicated the effect of celastrol on OVCAR3 cells and inhibited the PI3K/p‑Akt‑NF‑κB signaling pathway in an in vitro model of ovarian carcinoma. 27840916 2016
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 Biomarker disease BEFREE Inhibiting the PI3K/AKT pathway may be a useful treatment for ovarian carcinoma. 25216292 2014
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 GeneticVariation disease BEFREE Although many tumors presented a single lesion (28/93, of which 23 overexpressed PIK3CA, 1 overexpressed AKT and 4 had lost PTEN), many OC (35/93) presented multiple alterations within the PI3K pathway. 23408974 2013
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 AlteredExpression disease BEFREE Conditional suppression of functional p53 increased p110alpha transcripts, protein levels and PI3K activity in immortalized, non-tumorigenic ovarian surface epithelial (OSE) cells, the precursors of ovarian carcinoma. 18270270 2008