PLAT, plasminogen activator, tissue type, 5327

N. diseases: 392; N. variants: 7
Disease: Cerebral Hemorrhage ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Reduced estimated glomerular filtration rate is associated with stroke outcome after intravenous rt-PA: the Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement (SAMURAI) rt-PA registry. 21088392 2011
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Symptomatic intracerebral hemorrhage among eligible warfarin-treated patients receiving intravenous tissue plasminogen activator for acute ischemic stroke. 20212195 2010
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. 19095969 2009
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Symptomatic intracerebral hemorrhage and recanalization after IV rt-PA: a multicenter study. 18753474 2008
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials. 18369171 2008
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Intravenous recombinant tissue plasminogen activator improves arterial recanalization rates and reduces infarct volumes in patients with hyperdense artery sign on baseline computed tomography. 18346647 2008
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Assessment of suitability of thrombolysis in middle cerebral artery infarction: a proof of concept study of a stereologically-based technique. 17690543 2007
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Argatroban tPA stroke study: study design and results in the first treated cohort. 16908730 2006
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience. 16126134 2005
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Our findings suggest that endogenous tPA plays an important role in heparin-produced cerebral hemorrhage via MMP9 induction and activation. 16190367 2005
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Essential role of endogenous tissue plasminogen activator through matrix metalloproteinase 9 induction and expression on heparin-produced cerebral hemorrhage after cerebral ischemia in mice. 14630814 2004
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Therapeutic phenotype RGD Tissue plasminogen activator for the treatment of intraventricular hematoma: the dose-effect relationship. 12220690 2002
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. 11940547 2002
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study. 11113218 2000
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Brain hemorrhages after rt-PA treatment of embolic stroke in spontaneously hypertensive rats. 10501537 1999
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Thrombolysis with intravenous rtPA in a series of 100 cases of acute carotid territory stroke: determination of etiological, topographic, and radiological outcome factors. 9836764 1998
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Complications from the use of thrombolytic agents in patients with cocaine associated chest pain. 8969996 1997
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Tissue plasminogen activator for acute ischemic stroke. 7477192 1995
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Safety and efficacy of intravenous tissue plasminogen activator and heparin in acute middle cerebral artery stroke. 1579960 1992
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Severe acute myocardial infarction during a staphylococcal septicemia with meningoencephalitis. A possible contraindication to thrombolytic treatment. 1430592 1992
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.500 Biomarker phenotype CTD_human Intracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the Thrombolysis in Myocardial Infarction Study. Thrombolysis in Myocardial Infarction, Phase II, pilot and clinical trial. 1899364 1991