|
AA amyloidosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
CYC and etanercept (ETN) were administered to 62 and 24 RA patients, respectively, who were confirmed with biopsy as having AA amyloidosis.
|
22879465 |
2012 |
|
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
|
23535033 |
2014 |
|
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
|
23535033 |
2014 |
|
Angina, Unstable
|
0.010 |
Biomarker
|
disease |
BEFREE |
Eighty-four consecutive type 2 diabetic patients with unstable angina (UA) were included from January 2018 to June 2018 to calculate calcification scores using computerized tomographic angiography (CTA), and the patients were divided into 2 groups: high calcification score group (HCS group) and low calcification score group (LCS group).
|
31452690 |
2019 |
|
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Overall outcomes were comparable to those of two matched cohorts (n = 172) from previous European Vasculitis Society (EUVAS) trials, but with lower total exposure to CYC and GCs (P < 0.001) and reduced rates of severe infections (P = 0.02) compared with the RITUXVAS (rituximab versus cyclophosphamide in AAV) trial.
|
30239910 |
2019 |
|
Arterial aneurysm
|
0.010 |
Biomarker
|
disease |
BEFREE |
CYC and high dose glucocorticoids decreased mortality in pulmonary arterial aneurysms and postoperative complications in peripheral artery aneurysms.
|
30107448 |
2018 |
|
Behcet Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
CYC remains an important treatment option for Behçet's syndrome (BS) patients with life-threatening manifestations.
|
31840168 |
2019 |
|
Blood Platelet Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
This study of a family with the platelet disorder characterized by a defect of the platelet P2(CYC) receptor supports our hypothesis that the full complement of the platelet ADP receptors is essential for normal platelet secretion and that some patients with the common, ill-defined diagnosis of PSD are actually heterozygous for the defect.
|
11073862 |
2000 |
|
Bloom Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
We investigated short and long term adverse events associated with CYC use in BS patients.
|
31840168 |
2019 |
|
Brain Ischemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.
|
11756504 |
2002 |
|
Brain Stem Ischemia, Transient
|
0.300 |
Biomarker
|
disease |
CTD_human |
Manganese Superoxide Dismutase Affects Cytochrome c Release and Caspase-9 Activation After Transient Focal Cerebral Ischemia in Mice.
|
11333366 |
2001 |
|
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Chondrocytic HCS-2/8 cells and breast cancer MDA231 cells produce over 6 times more CCN2 than any other cell type.
|
17291666 |
2007 |
|
Carotid Circulation Transient Ischemic Attack
|
0.300 |
Biomarker
|
disease |
CTD_human |
Manganese Superoxide Dismutase Affects Cytochrome c Release and Caspase-9 Activation After Transient Focal Cerebral Ischemia in Mice.
|
11333366 |
2001 |
|
Cerebral Ischemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.
|
11756504 |
2002 |
|
Cervical intraepithelial neoplasia grade 2
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, the transcription of PCBP2, MCM5, hnRNPA1, TYPH, and CYC was also significantly increased in cervical intraepithelial neoplasia II-III compared to normal cervix.
|
28443473 |
2017 |
|
Chediak-Higashi Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
We used two human CHS cell lines SW1353 and HCS-2/8 to analyze the expression profiles of ADAM8 in CHS cells compared with the normal chondrocytes.
|
31305294 |
2019 |
|
Chloracne
|
0.300 |
Biomarker
|
disease |
CTD_human |
Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects.
|
17101203 |
2007 |
|
Chondrosarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated the effect of long-term exposure to 5% low oxygen atmosphere on human chondrosarcoma HCS-2/8 cells.
|
28865129 |
2018 |
|
Chondrosarcoma
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Meclozine also ameliorated abnormally suppressed proliferation of human chondrosarcoma (HCS-2/8) cells that were infected with lentivirus expressing constitutively active mutants of FGFR3-K650E causing thanatophoric dysplasia, FGFR3-K650M causing SADDAN, and FGFR3-G380R causing ACH.
|
24324705 |
2013 |
|
Chondrosarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
HCS-2/8 is a stable human chondrosarcoma cell line with many chondrocytic characteristics and has the capacity to form chondrosarcomas in nude mice.
|
8200849 |
1994 |
|
Chondrosarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Cell density-dependent proliferative effects of transforming growth factor (TGF)-beta 1, beta 2, and beta 3 in human chondrosarcoma cells HCS-2/8 are associated with changes in the expression of TGF-beta receptor type I.
|
11458815 |
2001 |
|
Chondrosarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
New clonal-cell lines HCS-TG C3 and E2 derived from human chondrosarcoma are morphologically chondrocytic in serial monolayer cultures and express chondrocytic phenotypes.
|
15118855 |
2004 |
|
Choriocarcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Chorionic somatomammotropin (hCS) genes (hCS-A and hCS-B) and the placental growth hormone variant (hGH-V) gene are expressed in the syncytiotrophoblast in vivo, and at low levels in cytotrophoblast-like choriocarcinoma (BeWo) cells.
|
8472847 |
1993 |
|
Choriocarcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Each individual concatenated enhanson was able to stimulate hCS promoter activity in an orientation-independent manner in choriocarcinoma cells (BeWo) with an observed stimulation that was directly proportional to its relative binding affinity for TEF-1 and CSEF-1.
|
9259314 |
1997 |
|
Choriocarcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
We demonstrated that TEF-1 represses hCS promoter activity in choriocarcinoma (BeWo) cells (Jiang, S.W., and Eberhardt, N.L.(1995) J. Biol.Chem.
|
8621623 |
1996 |