POLG, DNA polymerase gamma, catalytic subunit, 5428

N. diseases: 462; N. variants: 173
Disease: Mood Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.520 Biomarker group BEFREE POLG1 encodes mitochondrial DNA polymerase and is one of the causative genes for a Mendelian-inheritance mitochondrial disease, which is occasionally accompanied by mood disorders. 27987238 2017
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.520 Biomarker group PSYGENET Studies that focused on mood disorder comorbid with somatic symptoms, suggested roles for the mitochondrial DNA (mtDNA) 3644 mutation and the POLG mutation. 17239033 2007
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.520 GeneticVariation group LHGDN POLG mutations causing ophthalmoplegia, sensorimotor polyneuropathy, ataxia, and deafness. 14745080 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.520 Biomarker group MGD