PON1, paraoxonase 1, 5444

N. diseases: 496; N. variants: 29
Disease: Persian Gulf Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0282550
Disease: Persian Gulf Syndrome
Persian Gulf Syndrome 		0.330 GeneticVariation disease BEFREE Due to a reported possible twofold increased risk of ALS in Gulf War veterans and the associations of PON1 polymorphisms with the neurologic symptom complex of the Gulf War syndrome, the authors investigated the association between sporadic ALS (SALS) and PON gene cluster variants in a large North American Caucasian family-based and case-control cohort (N = 1,891). 16822964 2006
CUI: C0282550
Disease: Persian Gulf Syndrome
Persian Gulf Syndrome 		0.330 Biomarker disease BEFREE Our finding parallels others' observation of a link between PON1 heterozygosity and neurological symptoms in Gulf War syndrome. 15256524 2004
CUI: C0282550
Disease: Persian Gulf Syndrome
Persian Gulf Syndrome 		0.330 Biomarker disease CTD_human Association of low PON1 type Q (type A) arylesterase activity with neurologic symptom complexes in Gulf War veterans. 10373407 1999
CUI: C0282550
Disease: Persian Gulf Syndrome
Persian Gulf Syndrome 		0.330 GeneticVariation disease BEFREE The effect of PON1 polymorphisms on activity may also explain why some Gulf War Veterans have developed Gulf War Syndrome and some have not. 9313934 1997