Malignant neoplasm of stomach
|
0.400 |
Biomarker
|
disease |
BEFREE |
PPARγ played an important role as a physiological regulator and might be a target for the treatment of GC.
|
26956036 |
2016 |
Malignant neoplasm of stomach
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
PGDS is a potentially promising therapeutic agent for gastric cancers that express PPARγ.
|
25516376 |
2015 |
Malignant neoplasm of stomach
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The study suggests that the PPAR-γ Pro12Ala polymorphism could be evaluated as a potential genetic marker for susceptibility to gastric cancer in the presence of H. pylori infection.
|
26225656 |
2015 |
Malignant neoplasm of stomach
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
PPARγ expression in GCs was determined by immunohistochemical staining of tissue microarrays and survival analysis was done.
|
24976296 |
2015 |
Malignant neoplasm of stomach
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to comprehensively evaluate the PPARγ Pro12Ala polymorphism and gastric cancer susceptibility.
|
25824760 |
2015 |
Malignant neoplasm of stomach
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our results indicated PPAR-γ G allele may be an important contributor to non-cardia gastric cancer in Iranian H. pylori infected patients.
|
20568969 |
2010 |
Malignant neoplasm of stomach
|
0.400 |
Biomarker
|
disease |
CTD_human |
Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells.
|
19140230 |
2009 |
Malignant neoplasm of stomach
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells.
|
19140230 |
2009 |
Malignant neoplasm of stomach
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobacter pylori infection with gastric cancer and peptic ulcer disease (PUD).
|
18372284 |
2008 |
Malignant neoplasm of stomach
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We investigated the influence of PPARgamma gene Plo12Ala polymorphism on the risk of gastric cancer and on the severity of Helicobacter pylori-induced gastritis as well as impaired fasting glucose (IFG) in Japanese.
|
17763950 |
2008 |
Malignant neoplasm of stomach
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
To study the association between peroxisome proliferator-activated receptor gamma gene polymorphism, Helicobacter pylori infection and gastric cancer in Chinese.
|
16393309 |
2006 |
Malignant neoplasm of stomach
|
0.400 |
Biomarker
|
disease |
CTD_human |
Expression of tissue PPARgamma, tissue levels of IL-1beta and IL-8, and plasma concentration of gastrin were significantly higher in H. pylori-positive GC compared to controls, but H. pylori eradication significantly reduced these parameters.
|
15492468 |
2004 |
Malignant neoplasm of stomach
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Expression of tissue PPARgamma, tissue levels of IL-1beta and IL-8, and plasma concentration of gastrin were significantly higher in H. pylori-positive GC compared to controls, but H. pylori eradication significantly reduced these parameters.
|
15492468 |
2004 |
Malignant neoplasm of stomach
|
0.400 |
Biomarker
|
disease |
BEFREE |
The aim of the present study was 1) to examine the mRNA and protein expression of PPARgamma in gastric cancer (GC); 2) to evaluate the effect of PPARgamma ligand (ciglitazone) on the proliferation and apoptosis of GC cell line; and 3) to assess the levels of gastric tissue proinflammatory cytokines, IL-1beta and IL-8, and plasma gastrin in GC patients before and after Helicobacter pylori (H. pylori) eradication.
|
15492468 |
2004 |
Malignant neoplasm of stomach
|
0.400 |
Biomarker
|
disease |
BEFREE |
We examined the in vitro and in vivo effects of PPARgamma ligands on growth of gastric cancer, and the effect of PPARgamma activation on expression of cyclooxygenase 2 (COX-2) and cancer related genes.
|
14960510 |
2004 |
Malignant neoplasm of stomach
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We report the PPARgamma expression in human gastric cancer, and the effect of PPARgamma ligands on proliferation of gastric carcinoma cell lines.
|
11044367 |
2000 |