Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.300 Biomarker disease CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker disease BEFREE Hepatic specific silence of PPP1R3C provides a promising therapeutic strategy for type 2 diabetes. 31181215 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker disease MGD PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. 12727934 2003
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 Biomarker disease BEFREE The aim of the this study is to investigate the posttraumatic growth level of adults with type 2 diabetes and to identify the relationship among perceived social support, coping, diabetes management self-efficacy, perceived expressed emotions, and PTG in diabetes patients from non-western, developing country. 27115317 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 Biomarker group BEFREE The aim of the this study is to investigate the posttraumatic growth level of adults with type 2 diabetes and to identify the relationship among perceived social support, coping, diabetes management self-efficacy, perceived expressed emotions, and PTG in diabetes patients from non-western, developing country. 27115317 2019
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 GeneticVariation disease BEFREE Interestingly, five positional candidate genes for diabetes and related complications are located in our linkage region (the pituitary adenylate cyclase activating polypeptide (PACAP in 18p11); the peroxisome proliferator-activated receptor gamma coactivator 1 (PPARGC1 in 4p15); PTEN, PPP1R5, and IDE located in 10q23. 17548123 2007
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 GeneticVariation group BEFREE Interestingly, five positional candidate genes for diabetes and related complications are located in our linkage region (the pituitary adenylate cyclase activating polypeptide (PACAP in 18p11); the peroxisome proliferator-activated receptor gamma coactivator 1 (PPARGC1 in 4p15); PTEN, PPP1R5, and IDE located in 10q23. 17548123 2007
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 AlteredExpression disease BEFREE The phosphatase activity associated with R3E is slightly higher than that associated with R5/PTG and it is downregulated in streptozotocin-induced diabetes by 60-70% and restored by insulin treatment. 15752363 2005
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 AlteredExpression group BEFREE The phosphatase activity associated with R3E is slightly higher than that associated with R5/PTG and it is downregulated in streptozotocin-induced diabetes by 60-70% and restored by insulin treatment. 15752363 2005
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.010 Biomarker group BEFREE The aim of the present study was to establish whether in people struggling with cancer there is an association between the degree of PTG and the level of deliberate and intrusive ruminations, occurring soon after the diagnosis of disease and currently, and whether deliberate ruminations play a mediating role between intrusive ruminations and PTG. 31084411 2020
CUI: C0154575
Disease: Rumination Disorders
Rumination Disorders
0.010 Biomarker group BEFREE The aim of the present study was to establish whether in people struggling with cancer there is an association between the degree of PTG and the level of deliberate and intrusive ruminations, occurring soon after the diagnosis of disease and currently, and whether deliberate ruminations play a mediating role between intrusive ruminations and PTG. 31084411 2020
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker group BEFREE The aim of the present study was to establish whether in people struggling with cancer there is an association between the degree of PTG and the level of deliberate and intrusive ruminations, occurring soon after the diagnosis of disease and currently, and whether deliberate ruminations play a mediating role between intrusive ruminations and PTG. 31084411 2020
CUI: C0400966
Disease: Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease
0.010 Biomarker disease BEFREE Our data highlighted the role of PPP1R3C targeting pathways, and found that hepatic glycogen metabolism might be the potential target of LGZG in preventing NAFLD. 30616587 2019
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 Biomarker disease BEFREE Posttraumatic stress symptoms and PTG were assessed in 182 breast cancer survivors by using the Post-traumatic Stress Disorder Checklist and Post-traumatic Growth Inventory questionnaires. 29740909 2018
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.010 Biomarker disease BEFREE Posttraumatic stress symptoms and PTG were assessed in 182 breast cancer survivors by using the Post-traumatic Stress Disorder Checklist and Post-traumatic Growth Inventory questionnaires. 29740909 2018
CUI: C0278996
Disease: Malignant Head and Neck Neoplasm
Malignant Head and Neck Neoplasm
0.010 Biomarker disease BEFREE We investigated the extent of PTG, factors associated with PTG, and associations between PTG and health-related quality-of-life (HRQoL) in HNC survivors. 29473248 2018
CUI: C0521991
Disease: Symptoms of stress
Symptoms of stress
0.010 Biomarker phenotype BEFREE Posttraumatic stress symptoms and PTG show relationships with the amount of time spent online, the type of information accessed online, and the psychological impact of Internet use. 29740909 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.010 Biomarker disease BEFREE Posttraumatic stress symptoms and PTG were assessed in 182 breast cancer survivors by using the Post-traumatic Stress Disorder Checklist and Post-traumatic Growth Inventory questionnaires. 29740909 2018
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.010 Biomarker disease BEFREE We investigated the extent of PTG, factors associated with PTG, and associations between PTG and health-related quality-of-life (HRQoL) in HNC survivors. 29473248 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.010 Biomarker disease BEFREE This supports the concept that PTG is linked to coping as higher growth is reported with more stress, and that depression is a barrier to growth. 28784344 2017
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.010 Biomarker disease BEFREE This supports the concept that PTG is linked to coping as higher growth is reported with more stress, and that depression is a barrier to growth. 28784344 2017
CUI: C0015672
Disease: Fatigue
Fatigue
0.010 Biomarker phenotype BEFREE TRS instruments had lower resistance to cyclic fatigue and lower flexibility compared with PTG and PTN instruments. 27616210 2017
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.010 Biomarker phenotype BEFREE This supports the concept that PTG is linked to coping as higher growth is reported with more stress, and that depression is a barrier to growth. 28784344 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.010 AlteredExpression disease BEFREE Although PTG expression did not significantly affect the proliferation of HepG2 cells under normal culture conditions, we determined that PTG plays an important role during glucose deprivation. 26182369 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 PosttranslationalModification disease BEFREE In plasma samples, PPP1R3C was methylated in 81% (97/120) of CRC patients, but only in 19% (18/96) of noncancer patients (P = 6 × 10(-20) , Fisher's exact test). 24861485 2014