Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 Biomarker disease BEFREE Our study uncovers a novel function of AMPKα1 in redox regulation and identifies a promising therapeutic strategy for treatment of CRC. 31530934 2020
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 Biomarker disease BEFREE DT-13 inhibited the proliferation of colorectal cancer via glycolytic metabolism and AMPK/mTOR signaling pathway. 30668361 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 Biomarker disease BEFREE Here, we identify the AMPK-related kinase NUAK1 as a key component of the antioxidant stress response pathway and reveal a specific requirement for this role of NUAK1 in colorectal cancer. 29500295 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 Biomarker disease BEFREE α-enolase promotes tumorigenesis and metastasis via regulating AMPK/mTOR pathway in colorectal cancer. 27996156 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 GeneticVariation disease BEFREE AMPKα1 shRNA knockdown or dominant negative mutation abolished NPC-26-induced AMPK activation and subsequent CRC cell death. 28407688 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 Biomarker disease BEFREE Mesenchymal stem cells promote colorectal cancer progression through AMPK/mTOR-mediated NF-κB activation. 26892992 2016
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 AlteredExpression disease BEFREE Our aim was to investigate the expression changes of SIRT1-AMPK-autophagy pathway in the progression from chronic colitis to CRC. 27085036 2016
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.080 Biomarker disease BEFREE The present results suggest that genetic variants of the STK11, PRKAA1, and TSC1 genes could be used as prognostic biomarkers for patients with surgically resected colorectal cancer. 24770722 2014