MAPK8, mitogen-activated protein kinase 8, 5599

N. diseases: 520; N. variants: 4
Disease: Liver Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.320 Biomarker disease BEFREE Sab<sup>ΔHep</sup> mice or Jnk1+2<sup>ΔHep</sup> mice did not develop ALF following administration of VPA and APAP. 31029706 2019
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.320 Biomarker disease BEFREE We found in human and murine samples of ibuprofen-induced acute liver failure that JNK phosphorylation was increased in the cytoplasm of hepatocytes and other non-liver parenchymal cells (non-LPCs) compared with healthy tissue. 30264435 2019
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.320 Biomarker disease CTD_human Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure. 17185352 2007