|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Hereditary protein S (PS) deficiency is one of the natural anticoagulant deficiencies causing thrombophilia.
|
31422373 |
2020 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Analysis of PROC and PROS1 single nucleotide polymorphisms in a thrombophilia family.
|
31295762 |
2019 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
We processed 10,571 'thrombophilia' related test requests, including antithrombin (AT; n=3470), PC (n=3569), PS (n=3585), APCR (n=2359), factor V Leiden (FVL; n=2659), and prothrombin gene mutation (PGM; n=2103).
|
30485173 |
2019 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Thrombophilia due to protein C (PC) and protein S (PS) deficiencies is highly prevalent among patients with stage 5 chronic kidney disease and is reported to arise due to extracorporeal circulation during hemodialysis (HD).
|
31138132 |
2019 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Because individuals affected by the R338L mutation have normal concentrations of PS, we speculated that the Padua hypercoagulation phenotype is due to decreased inhibition of FIXa R338L by PS.
|
30189336 |
2018 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Detected with conventional laboratory tests high-risk thrombophilia was present in 70 patients: deficiencies of antithrombin (AT) (n = 12), protein C (PC) (n = 14), protein S (PS) (n = 6), homozygous factor V Leiden (FVL) mutation (n = 9) and combined types (n = 29).
|
29782332 |
2018 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The frequency of thrombophilia, such as antithrombin (AT), protein C (PC), or protein S (PS) gene mutations, was examined in 21 patients with PVT, 6 patients with SMVT, and 6 patients with both PVT and SMVT.
|
29747524 |
2018 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To identify inherited factors: Protein C (PC), protein S (PS), antithrombin (AT), plasminogen (Plg), the activated PC resistance (APCR), prothrombin (PT) mutation G20210 A (PTG20210 A) and methylenetetrahydrofolate reductase C677 T polymorphism (MTHFR C677 T), as well as acquired-risk factors such as: diabetes mellitus, surgeries, smoking, obesity, hypertension, trauma, alcoholism, family history; and their association, in Mexican patients with diagnostic of thrombophilia.
|
26315791 |
2015 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, we identified unique genomic architectures in the intervening sequences of PROS1 that underlie a large intragenic tandem duplication mutation leading to inherited thrombophilia.
|
24992033 |
2014 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Deficiencies of natural anticoagulant proteins including antithrombin (AT), protein C (PC) and protein S (PS) are important causes of inherited thrombophilia.
|
22627591 |
2012 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
In the Chinese population, PS and PC deficiencies are common thrombophilia for VTE during pregnancy and thrombophilia screening should be recommended in all pregnant women who suffer from VTE.
|
22398278 |
2012 |
|
Thrombophilia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Thrombophilia screening after the complete resolution consistently showed mildly decreased protein S (PS) activity with normal PS antigen levels.
|
21285903 |
2011 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Investigation for thrombophilia revealed protein S (PS) deficiency in this patient.
|
18434709 |
2008 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Because of the presence of a pseudogene and two different forms of PS in plasma, a bound and a free form, it is one of the most difficult thrombophilias to study.
|
18479427 |
2008 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
LHGDN |
Molecular basis of protein S deficiency.
|
17849042 |
2007 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
This article reviews the literature to understand PS and congenital PS deficiency, especially the association of this thrombophilia with pregnancy.
|
16026279 |
2005 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Hereditary protein S (PS) deficiency is a rare autosomal disorder of the coagulation pathway associated with familial thrombophilia.
|
12681974 |
2003 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Anticoagulant protein S (PS) deficiency is a known risk factor for thrombophilia.
|
10790208 |
2000 |
|
Thrombophilia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
A novel mutation in intron K of the PROS1 gene causes aberrant RNA splicing and is a common cause of protein S deficiency in a UK thrombophilia cohort.
|
9657428 |
1998 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Previously reported polymorphisms and point mutations leading to PS deficiency and thrombophilia have been analyzed with our structural predictions.
|
9408945 |
1997 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Both PC and PS deficiencies have been implicated in thrombophilia.
|
9241706 |
1997 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
BEFREE |
We studied the prevalence of antithrombin III (AT III), protein C (PC) and protein S (PS) deficiencies and factor V Leiden mutation in thrombophilia in Taiwan.
|
9271815 |
1997 |
|
Thrombophilia
|
0.200 |
Biomarker
|
disease |
HPO |
|
|
|