RETN, resistin, 56729

N. diseases: 302; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 AlteredExpression group BEFREE Data seem to suggest that lower levels of adiponectin, and higher levels of resistin can be predictive of a future diabetes in obese people, even years before the disease onset. 31811995 2020
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Both systemic and adipose tissue resistin are linked to dysglycemia in these individuals and may be a potential biomarker for diabetes in this population. 30778042 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE It has been suggested that resistin is a linkage between obesity, inflammation and type two diabetes. 31820685 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Further, resistin concentration was higher in PHEO patients with diabetes than in non-diabetic ones (p<0.001). 31738032 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE The adipokine resistin has been proposed to link obesity, insulin resistance and diabetes. 30353146 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 GeneticVariation group BEFREE Association of genetic variants in RETN, NAMPT and ADIPOQ gene with glycemic, metabolic traits and diabetes risk in a Chinese population. 29101068 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Several of these activities, together with the effect of ellagic acid on insulin, glycogen, phosphatases, aldose reductase, sorbitol accumulation, advanced glycation end-product formation, and resistin secretion, may explain its effects on metabolic syndrome and diabetes. 29847844 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Here, we summarized various molecular aspects are associated with DM particularly the molecular pathways involved in insulin resistance and resistin in DM. 28688216 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE A total of 422 patients with diabetes mellitus were recruited for this cross-sectional study to examine the association between resistin and intact FGF23. 30228288 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 AlteredExpression group BEFREE In experiments reported among different human genetic groups as well as the patients with various disease such as diabetes, no significant correlation is shown between FBG and resistin level. 29991083 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Resistin, a cysteine-rich peptide, is associated with atherosclerosis and diabetes. 29615544 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Adipose tissue is an important endocrine organ that secretes a number of adipokines, like Resistin (RETN); it's an adipocytes-secreted cytokine and has been proposed as a link between obesity and diabetes. 28393393 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 AlteredExpression group BEFREE Thirty-seven patients (35.6%) had high aortic stiffness and higher percentages of diabetes (p = 0.001), were of older age (p = 0.001) and had higher waist circumference (p < 0.001), systolic blood pressure (p = 0.027), pulse pressure (p = 0.013), high-sensitivity C-reactive protein (p < 0.001) and resistin levels (p < 0.001) but lower estimated glomerular filtration rate (p = 0.009) compared to subjects with low aortic stiffness. 28806778 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 AlteredExpression group BEFREE Two studies showed comparable resistin levels from GCF and serum between diabetes mellitus with CP (DMCP) and CP groups. 27567495 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 AlteredExpression group BEFREE Oligonol attenuated serum resistin and IL-6 levels and reduced glomerular hypertrophy and mesangial matrix expansion caused by diabetes. 26960417 2016
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE This finding suggested an essential role of resistin in linking IR and hypertension, which may offer a novel target in clinic on the study of the association between diabetes and hypertension. 26917360 2016
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Resistin may be an important link between obesity and diabetes. 25656506 2015
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 AlteredExpression group BEFREE Plasma resistin level is a potential molecular link between obesity and diabetes. 24123702 2014
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Further investigation of this association as well as of the actual biological roles of RETN in the genesis of human metabolic disorders including DM will be required. 23327840 2013
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Resistin, a cysteine-rich adipocytokine, proposed as a link between obesity and diabetes in mice, was shown as a proinflammatory molecule in humans. 24282299 2013
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE In this review knowledge on resistin, including its structure, physiological role related to obesity and diabetes, as well as, gene sequence and phenotypic effects of the identified polymorphisms in human and domestic mammals is discussed. 24152833 2013
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Resistin is an adipocyte-secreted cytokine recently discovered and has been proposed as a link between obesity and diabetes. 23020084 2012
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 AlteredExpression group BEFREE Furthermore, no significant association between higher resistin levels and diabetes mellitus 2, body mass index, smoking or age have been observed within studied groups. 21275461 2011
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 GeneticVariation group BEFREE Using comprehensive linkage disequilibrium mapping, we genotyped tag single nucleotide polymorphisms (SNPs) in RETN and tested associations with plasma resistin levels, risk of diabetes, and glycemic traits. 19074981 2009
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.100 Biomarker group BEFREE Resistin causes insulin resistance and diabetes in mice whereas in humans it is linked to inflammation and atherosclerosis. 18710472 2009