PTAFR, platelet activating factor receptor, 5724

N. diseases: 96; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.030 Biomarker disease BEFREE Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome. 30976089 2019
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.030 Biomarker disease BEFREE Biological pathways constructed using Cytoscape identified plausible biological links potentially leading to pneumonia downstream of TBXA2R and PTAFR. 29077727 2017
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.030 Biomarker disease BEFREE These data suggest that TLR2 is the single most important receptor signaling the presence of LTA within the lungs in vivo, whereas TLR4 and PAFR may influence lung inflammation induced by LTA either by sensing LTA directly or through recognition and signaling of endogenous mediators induced by the interaction between LTA and TLR2. 18292574 2008