Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014544
Disease: Epilepsy
Epilepsy
0.320 Biomarker disease BEFREE This second region comprises about 3 Mb and contains the candidate gene SLC4A10, providing further support for the potential role of this gene in epilepsy. 21204806 2010
CUI: C0014544
Disease: Epilepsy
Epilepsy
0.320 Biomarker disease BEFREE SLC4A10 is the third SLC4 base transporter family member to be implicated in human cognition and epilepsy. 18413482 2008
CUI: C0014544
Disease: Epilepsy
Epilepsy
0.320 Therapeutic disease CTD_human Hence, Slc4a10 is a promising pharmacological target for the therapy of epilepsy or elevated intracranial pressure. 18165320 2008
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.310 Biomarker group BEFREE Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability
0.310 Biomarker group CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders
0.300 Biomarker group CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0020796
Disease: Profound Mental Retardation
Profound Mental Retardation
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0025363
Disease: Mental Retardation, Psychosocial
Mental Retardation, Psychosocial
0.300 Biomarker phenotype CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0085541
Disease: Epilepsy, Frontal Lobe
Epilepsy, Frontal Lobe
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0086237
Disease: Epilepsy, Cryptogenic
Epilepsy, Cryptogenic
0.300 Therapeutic disease CTD_human Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. 18165320 2008
CUI: C0151740
Disease: Intracranial Hypertension
Intracranial Hypertension
0.300 Therapeutic disease CTD_human Hence, Slc4a10 is a promising pharmacological target for the therapy of epilepsy or elevated intracranial pressure. 18165320 2008
CUI: C0236018
Disease: Aura
Aura
0.300 Therapeutic phenotype CTD_human Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. 18165320 2008
CUI: C0393671
Disease: Frontal Epilepsy, Benign, Childhood
Frontal Epilepsy, Benign, Childhood
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0393683
Disease: Epilepsy, Supplementary Motor
Epilepsy, Supplementary Motor
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0393684
Disease: Epilepsy, Cingulate
Epilepsy, Cingulate
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0393688
Disease: Epilepsy, Opercular
Epilepsy, Opercular
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0751111
Disease: Awakening Epilepsy
Awakening Epilepsy
0.300 Therapeutic disease CTD_human Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. 18165320 2008
CUI: C0751642
Disease: Epilepsy, Anterior Fronto-Polar
Epilepsy, Anterior Fronto-Polar
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0751643
Disease: Epilepsy, Orbito-Frontal
Epilepsy, Orbito-Frontal
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0917816
Disease: Mental deficiency
Mental deficiency
0.300 Biomarker disease CTD_human Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. 18413482 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.110 GeneticVariation disease GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.110 GeneticVariation disease GWASCAT Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. 29483656 2018
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.110 GeneticVariation disease BEFREE Based on conjunctional FDR < 0.05, we identified 2 loci shared between SCZ and ICV implicating genes FOXO3 (rs10457180) and ITIH4 (rs4687658), 2 loci shared between SCZ and hippocampal volume implicating SLC4A10 (rs4664442) and SPATS2L (rs1653290), and 2 loci shared between SCZ and volume of putamen implicating DCC (rs4632195) and DLG2 (rs11233632). 29136250 2018
CUI: C0021704
Disease: Intelligence
Intelligence
0.100 GeneticVariation phenotype GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
CUI: C0021704
Disease: Intelligence
Intelligence
0.100 GeneticVariation phenotype GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019