PTGS2, prostaglandin-endoperoxide synthase 2, 5743

N. diseases: 1234; N. variants: 27
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.500 Biomarker disease RGD Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. 21718970 2011
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.500 Biomarker disease CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.500 Biomarker disease CTD_human Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. 17394460 2007
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.500 Biomarker disease CTD_human Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat. 15737438 2005
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.500 Biomarker disease CTD_human Nimesulide prevents oxidative stress damage following transient forebrain ischemia in the rat hippocampus. 17564305 2004
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.500 Biomarker disease RGD Cyclooxygenase-2 mRNA expression is associated with c-fos mRNA expression and transient water ADC reduction detected with diffusion MRI during acute focal ischemia in rats. 12535784 2003