PTHLH, parathyroid hormone like hormone, 5744

N. diseases: 321; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 AlteredExpression disease BEFREE Expression of parathyroid hormone-related protein (PTHrP) in multiple myeloma. 11940209 2002
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 Biomarker disease BEFREE The fundamental role of PTHrP in bone lesions and hypercalcemia in myeloma may be important to consider even during the initial phase of the disease and particularly in the progression of bone complications with hypercalcemia. 11378553 2001
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 AlteredExpression disease BEFREE Assessment of cellular expression of parathyroid hormone-related protein mRNA and protein in multiple myeloma. 11054717 2000
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 Biomarker disease CTD_human The present findings are consistent with the view that PTHrP can be generated in myeloma cells in vivo, and could contribute to osteolysis and hypercalcaemia, as in patients with cancer. 11054717 2000
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 Biomarker disease BEFREE PTHrP has been measured as elevated in the plasma of patients with myeloma and might be an important contributor to the skeletal complications in this disease. 9783553 1998
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 Biomarker disease BEFREE These findings indicate that PTH-rP may be one of the factors responsible for the bone destruction or hypercalcemia in multiple myeloma. 8250014 1994