Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Relatively weak inducible IFN-β production in HBV infected patients with IPS-1 rs7269320 SNP or wild-type may contribute to chronic virus infection.
|
30930359 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
RNF34 binds to MAVS in the mitochondrial compartment after viral infection and negatively regulates RIG-I-like receptor (RLR)-mediated antiviral immunity.
|
31304625 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
GoMAVS inhibited Newcastle disease virus replication by activating type I IFN pathways, especially at the early stages of infection.
|
30557581 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Their active forms activate mitochondrial antiviral signaling protein (MAVS) and trigger downstream immune responses against viral infection.
|
30569868 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
NAC1 was able to interact with MAVS and TBK1 upon viral infection.
|
31235549 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS.
|
30410068 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Here, we show that NLK inhibits the antiviral immune response during viral infection by targeting MAVS for degradation.
|
31324787 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Viral infection causes the aggregation of VISA, which is important for its recruitment of downstream signaling components.
|
31511639 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
YOD1 was recruited to mitochondria to interact with MAVS through its UBX and Znf domains after viral infection.
|
30952814 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The interaction of FKBP8 with VISA, retinoic acid inducible protein 1 (RIG-I), and IFN regulatory factor 3 (IRF3) was confirmed during viral infection in mammalian cells by coimmunoprecipitation.
|
30267576 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In this study, we found that Newcastle disease virus (NDV) infection induced MAVS degradation.
|
31270229 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection.
|
30472208 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Here, we describe a novel method of visualizing and quantifying the aggregation of MAVS in response to dsRNA stimulation or viral infection in vitro using confocal microscopy.
|
29177867 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The collective results of this study suggest a novel regulation mechanism of MAVS-mediated immunity during RNA viral infection by miR-3570.
|
29093090 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The mitochondrial adaptor molecule MAVS plays a critical role in innate immune response to viral infection.
|
29743353 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
MAVS forms prion-like aggregates on the mitochondria after virus infection.
|
29245018 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Taken together, these results suggest that ASC, as a negative regulator of the MAVS-mediated innate immunity, may play an important role in host protection upon virus infection.
|
29280086 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
This modification promoted the formation of prion-like aggregates of MAVS after viral infection.
|
27992402 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Here, we report NLRP11, a Nod-like receptor, is induced by type I IFN and translocates to mitochondria to interact with MAVS upon viral infection.
|
29097393 |
2017 |
Virus Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Whereas NLRX1 suppressed MAVS-mediated activation of IRF3, it conversely facilitated virus-induced increases in IRF1 expression and thereby enhanced control of viral infection.
|
28967880 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Although monomeric MAVS recombinant protein can assemble into prion-like filaments spontaneously in vitro, endogenous MAVS in cells is prevented from aggregation until viral infection.
|
28607490 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Virus infection promotes the mitochondrial localization of TAX1BP1 and concomitant interaction with the mitochondrial adaptor MAVS.
|
27736772 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Maintenance of VISA stability by iRhom2 ensures efficient innate antiviral response at the early phase of viral infection and ready for next round of response.
|
29155878 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Interestingly, following NF-κB activation upon virus infection, CARMA3 is targeted for proteasome-dependent degradation, which releases MAVS to activate IRF3.
|
26947079 |
2016 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mitochondrial membrane protein MAVS to induce innate immunity to viral infection through type I interferon production.
|
26317833 |
2015 |