PXN, paxillin, 5829

N. diseases: 116; N. variants: 5
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.020 AlteredExpression disease BEFREE With the PI3K/AKT pathway inhibited, down-regulated paxillin suppressed colon cancer cell proliferation and invasion by inhibiting the M2 macrophage polarization, thereby restraining the tumor progression. 29924724 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.020 Biomarker disease BEFREE Moreover, similarly increased paxillin pY88 is also found as a common feature of human colon cancers. 20133777 2010