Disease: Cutaneous Melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 Biomarker disease BEFREE We conclude that loss of NF1 is common in cutaneous melanoma and is associated with RAS activation, MEK-dependence, and resistance to RAF inhibition. 24576830 2014
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation disease BEFREE To investigate the mechanism(s) of resistance to the RAF-inhibitor vemurafenib, we conducted a comprehensive analysis of the genetic alterations occurring in metastatic lesions from a patient with a BRAF(V600E)-mutant cutaneous melanoma who, after a first response, underwent subsequent rechallenge with this drug. 23948972 2013
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation disease BEFREE RAS and RAF mutations in banal melanocytic aggregates contiguous with primary cutaneous melanoma: clues to melanomagenesis. 18945298 2009
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 AlteredExpression disease BEFREE Constitutive activation of the RAS-RAF-MEK-ERK signaling cascade is a hallmark of cutaneous malignant melanoma. 16007203 2005
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 CausalMutation disease CGI