RB1, RB transcriptional corepressor 1, 5925

N. diseases: 339; N. variants: 239
Disease: Small cell carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 AlteredExpression disease BEFREE Furthermore, expression of the retinoblastoma 1 (RB1) gene protein was lost in most of the bladder SmCCs (2/23). 29763719 2018
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 GeneticVariation disease BEFREE In addition, we observed that the mutation rate was significantly higher in samples with RB1 gene mutated when compared to samples with wild type RB1, suggesting that RB1 status has significant impact on the mutation profile and disease progression in SCLC. 29025592 2017
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 SomaticCausalMutation disease ORPHANET Comprehensive genomic profiles of small cell lung cancer. 26168399 2015
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 GeneticVariation disease CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 Biomarker disease CTD_human Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. 22941189 2012
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 Biomarker disease CTD_human Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. 22941188 2012
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 CausalMutation disease CGI
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 GenomicAlterations disease CGI
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.720 CausalMutation disease CLINVAR