|
Thyroid Neoplasm
|
0.400 |
Biomarker
|
disease |
BEFREE |
The aim of the study was to investigate the roles of long non-coding RNA (lncRNA) NR2F1-AS1/miRNA-338-3P/CCND1 axis in TC progression.
|
31304680 |
2019 |
|
Thyroid Neoplasm
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In our TC xenograft model, the combination of Vemurafenib and Bortezomib significantly reduced tumor size (<i>P</i> < 0.05) and expression of the markers of cell growth and proliferation, Ki-67 and cyclin D1 (<i>P</i> < 0.001), when compared to monotherapy.
|
29269566 |
2018 |
|
Thyroid Neoplasm
|
0.400 |
Biomarker
|
disease |
BEFREE |
CCND1 Splice Variant as A Novel Diagnostic and Predictive Biomarker for Thyroid Cancer.
|
30428594 |
2018 |
|
Thyroid Neoplasm
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Analyses showed that JQ1 decreased MYC abundance in thyroid tumors and attenuated the cyclin D1-CDK4-Rb-E2F3 signaling to decrease tumor growth.
|
27440272 |
2017 |
|
Thyroid Neoplasm
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cyclin D1 in well differentiated thyroid tumour of uncertain malignant potential.
|
25907675 |
2015 |
|
Thyroid Neoplasm
|
0.400 |
Biomarker
|
disease |
CTD_human |
Cancer-related genes transcriptionally induced by the fungicide penconazole.
|
23811263 |
2014 |
|
Thyroid Neoplasm
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Consistently, the aberrant elevation of PITX2 levels in the thyroid cancer of TRbeta(PV/PV) mice was accompanied by upregulation of Cyclin D1, Cyclin D2 and increased phosphorylation of Rb.
|
20372070 |
2010 |
|
Thyroid Neoplasm
|
0.400 |
Biomarker
|
disease |
LHGDN |
Array-CGH identifies cyclin D1 and UBCH10 amplicons in anaplastic thyroid carcinoma.
|
18753363 |
2008 |
|
Thyroid Neoplasm
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease?
|
17906980 |
2008 |
|
Thyroid Neoplasm
|
0.400 |
Biomarker
|
disease |
LHGDN |
The cytoplasmic expression of MUC1 in papillary thyroid carcinoma of different histological variants and its correlation with cyclin D1 overexpression.
|
17916995 |
2007 |
|
Thyroid Neoplasm
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
The level of cyclin D1 gene expression was significantly higher in malignant thyroid tumours (PTC, MTC), as compared with that in macroscopically unchanged thyroid tissue, FA and/or NG groups.
|
17693985 |
2007 |
|
Thyroid Neoplasm
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression.
|
17188136 |
2006 |
|
Thyroid Neoplasm
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
This study suggests that both cyclin D1 overexpression and aberrant beta-catenin expression are of significance in thyroid tumours.
|
15095272 |
2004 |
|
Thyroid Neoplasm
|
0.400 |
Biomarker
|
disease |
BEFREE |
Overexpression of the CCND1 gene was observed in both the benign and malignant thyroid tumors, whereas the ERBB2 gene was mainly overexpressed in malignant thyroid tumors.
|
11288983 |
2001 |
|
Thyroid Neoplasm
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Neither major genetic alterations nor amplifications for cyclin D1 and cyclin E genes were found by Southern blot analysis in genomic DNAs extracted from all types of thyroid tumors.
|
9626345 |
1998 |
|
Thyroid Neoplasm
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we examined the cyclin D1 gene expression and amplification in 24 tumor samples (two of them are benign goiters) randomly selected from the same series of thyroid tumors, to see whether cyclin D1 overexpression is present in those specimens without Rb gene mutations.
|
9666346 |
1998 |