RELA, RELA proto-oncogene, NF-kB subunit, 5970

N. diseases: 483; N. variants: 11
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 AlteredExpression group BEFREE Breast tumors expressing high levels of NF-κB p65 exhibited increased expression of Notch1. 24970818 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker group BEFREE These are overexpressed in breast tumors and regulate genes important for cancer cell survival and inflammation such as the p65 unit of NF-κB. 22941571 2012
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker group CTD_human BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells. 20154269 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker group LHGDN NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. 12690099 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker group LHGDN Estrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independence. 12972607 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker group LHGDN Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780). 12067985 2002
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker group HPO