REN, renin, 5972

N. diseases: 721; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0342443
Disease: Adrenal Cushing's syndrome
Adrenal Cushing's syndrome
0.040 Biomarker disease BEFREE The 10 patients with CS were divided in those with suppressed and nonsuppressed renin-angiotensin-aldosterone system (RAAS; n = 5 per group). 29726949 2018
CUI: C0342443
Disease: Adrenal Cushing's syndrome
Adrenal Cushing's syndrome
0.040 Biomarker disease BEFREE The objective of the present study was to investigate in vitro the effect of serotonin (5-hydroxy tryptamine; 5-HT) on cortisol and renin production by a left adrenocortical carcinoma removed from a 48-year-old female patient with severe Cushing's syndrome and elevated plasma renin levels. 18708508 2008
CUI: C0342443
Disease: Adrenal Cushing's syndrome
Adrenal Cushing's syndrome
0.040 Biomarker disease BEFREE The regulation of cortisol or aldosterone production when ACTH of pituitary origin or the renin-angiotensin systems are suppressed in primary adrenal Cushing's syndrome or in primary aldosteronism is exerted by diverse genetic and molecular mechanisms. 29678284 2018
CUI: C0342443
Disease: Adrenal Cushing's syndrome
Adrenal Cushing's syndrome
0.040 AlteredExpression disease BEFREE The relation between serum cortisol, plasma renin activity, angiotensin II (Ang II), or aldosterone levels and peripheral blood cell (mononuclear leukocytes and platelets) angiotensin II type 1A (AT1A) and 1B (AT1B) receptor mRNA levels was examined in both patients with Cushing's syndrome (seven patients with Cushing's syndrome due to unilateral adrenal cortical adenoma) and control subjects (seven normotensive patients with renal cell carcinoma). 7490136 1995