Mental Depression
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
Brain insulin signaling is accounted for the development of a variety of neuropsychiatric disorders, such as anxiety and depression, whereas both inflammation and the activated renin-angiotensin system (RAS) are two major contributors to insulin resistance.
|
31001119 |
2019 |
Mental Depression
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
Decreased level of BDNF is observed in depression and its connection to hypertension has also been demonstrated with affecting the arterial baroreceptors, renin-angiotensin system and endothelial nitric oxide synthase.
|
30767081 |
2019 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
BEFREE |
The results revealed that HO-1 and renin precursor (Rep) were independent factors that affected hypertension complicated with depression.
|
31410134 |
2019 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
BEFREE |
These findings emphasize the potential impact of depression on the low renin-hypertension phenotype in Blacks in terms of diagnosis and treatment.
|
29960014 |
2018 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
BEFREE |
Drugs targeting the renin-angiotensin system act on inflammatory pathways implicated in depression.
|
28760142 |
2017 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
BEFREE |
The importance of renin-angiotensin system (RAS) elements in cognition and behaviour and their involvement in aetiology and treatment of depression imply that RAS gene polymorphism(s) associated with RAS overactivity might also be associated with depression.
|
22688325 |
2012 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
PSYGENET |
The importance of renin-angiotensin system (RAS) elements in cognition and behaviour and their involvement in aetiology and treatment of depression imply that RAS gene polymorphism(s) associated with RAS overactivity might also be associated with depression.
|
22688325 |
2012 |
Mental Depression
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Four single nucleotide polymorphisms in the central serotonin system and the renin-angiotensin system related genes previously found to be associated with suicide, alcohol dependence or depression were genotyped.
|
19734157 |
2010 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
PSYGENET |
Four single nucleotide polymorphisms in the central serotonin system and the renin-angiotensin system related genes previously found to be associated with suicide, alcohol dependence or depression were genotyped.
|
19734157 |
2010 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
PSYGENET |
Renin-angiotensin-system gene polymorphisms and depression.
|
17499413 |
2007 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
PSYGENET |
Regarding the multiple interactions in the mechanisms between depression and cardiovascular system disorders, e.g., dysfunctions in the hypothalamic-pituitary-adrenocortical and sympathoadrenal axis and the response to stress, the importance of the serotonergic and immune systems, or the impact on the renin-angiotensin system, several candidate genes are being investigated.
|
17506223 |
2007 |
Mental Depression
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Renin-angiotensin-system gene polymorphisms and depression.
|
17499413 |
2007 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
BEFREE |
Regarding the multiple interactions in the mechanisms between depression and cardiovascular system disorders, e.g., dysfunctions in the hypothalamic-pituitary-adrenocortical and sympathoadrenal axis and the response to stress, the importance of the serotonergic and immune systems, or the impact on the renin-angiotensin system, several candidate genes are being investigated.
|
17506223 |
2007 |
Mental Depression
|
0.390 |
Biomarker
|
disease |
PSYGENET |
These results suggest that blockade of the renin-angiotensin system may increase the abundance of mRNA for SR proteins and, thus, may prevent the depression in SR Ca(2+) transport and improve cardiac function in congestive heart failure due to MI.
|
15576437 |
2005 |