REN, renin, 5972

N. diseases: 721; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 AlteredExpression disease BEFREE Assessment of the renin-angiotensin system (RAS) demonstrated that the ATRQβ-001 vaccine did not cause obvious feedback of circulating RAS, but prominently attenuated the expression of AT<sub>1</sub>R, compared with the other groups at 4 and 12 weeks after AMI. 30587854 2019
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 Biomarker disease BEFREE Impact of renin-angiotensin system inhibitors on long-term clinical outcomes in patients with acute myocardial infarction treated with successful percutaneous coronary intervention with drug-eluting stents: Comparison between STEMI and NSTEMI. 30529829 2019
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 Biomarker disease BEFREE Results of the subgroup analysis suggested that the intermediate-acting dihydropyridine calcium channel blocker was associated with higher risk of heart failure (RR: 1.30, [95% CI, 1.08-1.56], P = .005) and AMI (RR: 1.50, [95% CI, 1.01-2.22], P = .043) compared to renin-angiotensin system blockers and a trend toward higher risk of AMI (RR: 1.17, [95% CI, 0.99-1.38], P = .064) compared to conventional therapy, including β-blockers and diuretics. 29739234 2018
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 Biomarker disease BEFREE Renin-angiotensin-aldosterone system inhibitors (RASIs) are widely used in high-risk cardiovascular (CV) diseases, including acute myocardial infarction (AMI). 30130974 2018
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 GeneticVariation disease BEFREE Renin-angiotensin-aldosterone system polymorphisms and 5-year mortality in survivors of acute myocardial infarction: a report from the Osaka Acute Coronary Insufficiency Study. 24806378 2014
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 GeneticVariation disease BEFREE Renin-angiotensin-aldosterone system polymorphisms: a role or a hole in occurrence and long-term prognosis of acute myocardial infarction at young age. 17519002 2007
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 GeneticVariation disease BEFREE There have been many reports regarding the association between renin-angiotensin system (RAS) gene polymorphisms and coronary artery disease (CAD) or acute myocardial infarction (AMI), but the results are inconsistent. 17118372 2007
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.080 GeneticVariation disease BEFREE Three-gene interactions among the genetic polymorphisms of the renin-angiotensin system (RAS) associated with acute myocardial infarction (AMI) have not been examined in a single population. 16061119 2005