REN, renin, 5972

N. diseases: 721; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0221043
Disease: Liddle Syndrome
Liddle Syndrome
0.350 AlteredExpression disease BEFREE We collected laboratory data including concentration of serum potassium, plasma activity of renin and aldosterone, and residual blood and/or urine samples of participants who had experienced symptoms/signs of pseudoaldosteronism in the form of increase in blood pressure and occurrence or aggregation of oedema while taking liquorice-containing herbal preparations, and measured GL metabolites using a highly selective liquid chromatography tandem mass spectrometer system. 31605160 2019
CUI: C0221043
Disease: Liddle Syndrome
Liddle Syndrome
0.350 GeneticVariation disease BEFREE Liddle's syndrome appears to be the most common low-renin Mendelian hypertension in young Chinese hypertensive patients. 28915228 2018
CUI: C0221043
Disease: Liddle Syndrome
Liddle Syndrome
0.350 Biomarker disease BEFREE Severe and reproducible low-renin hypertension responsive to salt restriction and amiloride-thiazide therapy in a 13-year-old otherwise asymptomatic boy suggested Liddle syndrome. 21956615 2012
CUI: C0221043
Disease: Liddle Syndrome
Liddle Syndrome
0.350 Biomarker disease BEFREE Low-renin hypertension responsive to amiloride-thiazide therapy in a 4-year-old Afro-Haitian girl suggested Liddle syndrome. 15690192 2005
CUI: C0221043
Disease: Liddle Syndrome
Liddle Syndrome
0.350 Biomarker disease CTD_human Liddle syndrome in a newborn infant. 12185466 2002
CUI: C0221043
Disease: Liddle Syndrome
Liddle Syndrome
0.350 Biomarker disease BEFREE Renin and aldosterone secretion is often lower in blacks than in whites, characteristics that resemble a milder form of Liddle syndrome in which a mutation in the amiloride-sensitive epithelial sodium channel (ENaC) of the kidney results in enhanced resorption of sodium. 10523338 1999