UPF1, UPF1 RNA helicase and ATPase, 5976

N. diseases: 38; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.070 AlteredExpression disease BEFREE The results of the present study revealed that UPF1 was significantly downregulated in an HCC cell line. 30628676 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.070 Biomarker disease BEFREE Knockdown of UCA1 ameliorated the effect of UPF1 knock down on HCC growth and invasion. 31040354 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.070 Biomarker disease BEFREE Taken together, these findings showed that SNAI3-AS1 promotes the progression of HCC by regulating the UPF1 and activating TGF-β/Smad pathway. 31264769 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.070 AlteredExpression disease BEFREE In clinical samples of HCC, miR-1468 inversely correlated with the levels of CITED2 and UPF1, which were confirmed to be down-regulated in HCC. 29510736 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.070 Biomarker disease BEFREE These findings establish UPF1 as a potential therapeutic target for HCC patients. 28554132 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.070 Biomarker disease BEFREE Functionally, UPF1 regulated HCC tumorigenesis both in vitro and in vivo. 26759305 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.070 Biomarker disease BEFREE Upregulation of SNHG6 regulates ZEB1 expression by competitively binding miR-101-3p and interacting with UPF1 in hepatocellular carcinoma. 27702662 2016