BACH2, BTB domain and CNC homolog 2, 60468

N. diseases: 130; N. variants: 33
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018213
Disease: Graves Disease
Graves Disease
0.120 GeneticVariation disease BEFREE Our study clearly demonstrated that BACH2 is a susceptibility gene for GD in the Chinese Han population and further supported rs2474619, in intron 2 of BACH2, is the best association signal with GD. 24346624 2014
CUI: C0018213
Disease: Graves Disease
Graves Disease
0.120 GeneticVariation disease BEFREE The MAGI3 and BACH2 variants were associated with an increased risk of hyperthyroidism, which was replicated in an independent cohort of patients with Graves' disease (OR: 1.37, 95% CI 1.22-1.54, P = 1.2×10(-7) and OR: 1.25, 95% CI 1.12-1.39, P = 6.2×10(-5)). 24586183 2014
CUI: C0018213
Disease: Graves Disease
Graves Disease
0.120 GeneticVariation disease GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229 2012