S100A2, S100 calcium binding protein A2, 6273

N. diseases: 72; N. variants: 2
Disease: Squamous cell carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 AlteredExpression disease BEFREE Five studies evaluated S100A2, A7 and A12 and showed overexpression of these protein levels in OSCC patients when compared to healthy controls. 29453969 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 Biomarker disease BEFREE The intracellular localization of S100A2, A6, A8, A9, A10 and A11 protein was determined in normal corneal-limbal and SCC tissues. 21897749 2011
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 AlteredExpression disease BEFREE Analysis of S100A2 expression revealed that expression in adenocarcinomas and squamous cell carcinomas is significantly different, but not related to any of the found alterations. 18656279 2009
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 AlteredExpression disease BEFREE There was a significant difference in the average expression levels in S100A2 for ADC and SCC. 19238334 2009
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 AlteredExpression disease LHGDN Down-regulation of S100A2 in lymph node metastases of head and neck cancer. 17123307 2007
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 Biomarker disease BEFREE Although the interplay between S100A2 and COX-2 remains to be clarified, these findings first showed a potent antitumor role of S100A2 in squamous cell carcinoma partly via reduced expression of COX-2. 16908593 2006
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 AlteredExpression disease BEFREE The expression of nuclear S100A2 protein examined by immunohistochemistry was not significantly associated with any patient characteristic among the 70 early-stage oral squamous cell carcinoma (SCC) patients. 15792606 2005
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 AlteredExpression disease LHGDN Expression and prognostic significance of S100A2 protein in squamous cell carcinoma of the esophagus. 11956617 2002
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.090 Biomarker disease BEFREE S100A2, a putative tumor suppressor gene, regulates in vitro squamous cell carcinoma migration. 11304580 2001