S100B, S100 calcium binding protein B, 6285

N. diseases: 599; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group BEFREE This review addresses this novel scenario, presenting data indicating that S100B levels and/or distribution in the nervous tissue of patients and/or experimental models of different neural disorders, for which the protein is used as a biomarker, are directly related to the progress of the disease: acute brain injury (ischemic/hemorrhagic stroke, traumatic injury), neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis), congenital/perinatal disorders (Down syndrome, spinocerebellar ataxia-1), psychiatric disorders (schizophrenia, mood disorders), inflammatory bowel disease. 30144068 2019
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group BEFREE To review the literature investigating the role of S100B in patients with affective disorders. 29764272 2018
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group PSYGENET Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. 20962330 2010
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 Biomarker group PSYGENET Disturbance of these neurodevelopmental processes is proposed as one of the etiologies for mood disorder, and genetic polymorphisms of S100B have a possibility to be in susceptibility to major depressive disorder (MDD). 18939940 2008
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.330 GeneticVariation group LHGDN Candidate gene analysis of 21q22: support for S100B as a susceptibility gene for bipolar affective disorder with psychosis. 17525977 2007