SAA1, serum amyloid A1, 6288

N. diseases: 188; N. variants: 6
Disease: Amyloid nephropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0268382
Disease: Amyloid nephropathy
Amyloid nephropathy 		0.140 GeneticVariation disease BEFREE Indeed, the SAA1 alpha homozygous genotype and the p.Met694Val homozygous genotype at the MEFV locus are two main risk factors for RA. 19888326 2009
CUI: C0268382
Disease: Amyloid nephropathy
Amyloid nephropathy 		0.140 GeneticVariation disease BEFREE Evaluation of the risk factors, and phenotype-genotype correlation of familial Mediterranean fever (FMF) gene (MEFV) and serum amyloid A1 (SAA1) gene polymorphisms in renal amyloidosis. 16118480 2005
CUI: C0268382
Disease: Amyloid nephropathy
Amyloid nephropathy 		0.140 Biomarker disease BEFREE The SAA1 13T allele was rare, being associated mainly with the SAA gamma isoform, and not related to renal amyloidosis. 12687559 2003
CUI: C0268382
Disease: Amyloid nephropathy
Amyloid nephropathy 		0.140 GeneticVariation disease BEFREE Overall, these data, which provide new insights into the pathophysiology of FMF, demonstrate that susceptibility to renal amyloidosis in this Mendelian disorder is influenced by at least two MEFV-independent factors of genetic origin-SAA1 and sex-that act independently of each other. 11017802 2000
CUI: C0268382
Disease: Amyloid nephropathy
Amyloid nephropathy 		0.140 Biomarker disease HPO