Disease: Atrial Fibrillation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.040 GeneticVariation disease BEFREE We and others identified loss-of-function mutations in SCN1B and SCN2B and dominant-negative mutations in SCN3B in patients with AF. 30821358 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.040 GeneticVariation disease BEFREE Mutations in the cardiac sodium channel α, β1, β2 and β3 subunit genes (SCN5A, SCN1B, SCN2B and SCN3B) have been associated with AF, which suggests that mutations in the sodium channel β4 subunit gene, SCN4B, are also involved in the pathogenesis of AF. 23604097 2013
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.040 Biomarker disease BEFREE Mutations in cardiac sodium channel alpha, beta1 and beta2 subunit genes (SCN5A, SCN1B, and SCN2B) have been identified in AF patients. 20558140 2010
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.040 GeneticVariation disease BEFREE We identified 2 nonsynonymous variants in SCN1B (resulting in R85H, D153N) and 2 in SCN2B (R28Q, R28W) in patients with AF. 19808477 2009