Disease: Behcet Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 GeneticVariation disease BEFREE Our results suggest that the association of MEFV with BD could be modulated by the HLA molecules; whereas the protective effect of NOD2 p.Arg702Trp would be independent of HLA. 30808881 2019
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 Biomarker disease BEFREE Computational methods have captured pertinent features of the prominent disease characteristics presented in Behçet's disease and have highlighted NOD2, ICOS and IL18 signalling as potential therapeutic strategies. 27791955 2017
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 Biomarker disease BEFREE To analyze the role of NOD1 and NOD2 in the pathogenesis of Vogt- Koyanagi-Harada (VKH) syndrome and Behcet's disease (BD). 26980698 2016
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 GeneticVariation disease BEFREE In the current study of Behçet disease (BD), nonsynonymous variants (NSVs) identified by deep exonic resequencing of 10 genes found by GWAS (IL10, IL23R, CCR1, STAT4, KLRK1, KLRC1, KLRC2, KLRC3, KLRC4, and ERAP1) and 11 genes selected for their role in innate immunity (IL1B, IL1R1, IL1RN, NLRP3, MEFV, TNFRSF1A, PSTPIP1, CASP1, PYCARD, NOD2, and TLR4) were evaluated for BD association. 23633568 2013
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 GeneticVariation disease BEFREE MEFV, TNFRSF1A and CARD15 mutation analysis in Behçet's disease. 21385537 2011
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 Biomarker disease BEFREE Low prevalence of NOD2 SNPs in Behçet's disease suggests protective association in Caucasians. 19748964 2009
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 GeneticVariation disease BEFREE None of the three CARD15 variants predisposing to CD was observed in patients with BD, including two patients with intestinal involvement. 15515785 2005
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 GeneticVariation disease BEFREE Given certain clinical and pathological similarities between CD and BD, and recent evidence of linkage of BD to the CARD15 genomic region, the aim of this study was to investigate the role of CARD15 variants in determining susceptibility to BD. 16134731 2005
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.180 CausalMutation disease CLINVAR