Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease BEFREE In line with these findings, host variations in additional genes involved in host response to norovirus infection (such as ATG16L1 and NOD2) predispose humans to Crohn's ileitis. 24351661 2014
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human NOD2-associated diseases: Bridging innate immunity and autoinflammation. 19467619 2010
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. 18438406 2008
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human NOD2/CARD15 gene variants are linked to failure of antibiotic treatment in perianal fistulating Crohn's disease. 18371140 2008
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756 2007
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human Cell culture models in developing nutrigenomics foods for inflammatory bowel disease. 17568627 2007
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 GeneticVariation disease BEFREE In summary, CARD15 variant-associated Crohn's ileitis is virtually committed to stricturing and/or penetrating disease and, eventually, to resective surgery. 16167972 2005
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 AlteredExpression disease BEFREE Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. 14570728 2003
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. 11385577 2001
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human CARD15 mutations in Blau syndrome. 11528384 2001
CUI: C0267380
Disease: Crohn's disease of the ileum
Crohn's disease of the ileum
0.330 Biomarker disease CTD_human Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. 11385576 2001