Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 GeneticVariation disease BEFREE Our meta-analysis revealed that the <i>MKK4</i> -1304T>G polymorphism could reduce the risk of CRC (G <i>vs</i>. 31157265 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 Biomarker disease BEFREE These results suggest that CRC patients with low pMKK4 immunochemistry scores should be monitored carefully for early detection of possible recurrences, especially liver metastasis. 28423721 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 GeneticVariation disease BEFREE Functional polymorphism MKK4 -1304T>G has been showed to be protective in colorectal cancer or lung cancer. 21702039 2012
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 AlteredExpression disease BEFREE Western blotting analysis showed that the levels of Mkk4 protein in sporadic CRC neoplastic tissues were significantly higher in the carriers of -1304G variant genotypes than that in those with -1304TT genotypes. 19610067 2009