Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma
0.030 Biomarker disease BEFREE This is the first study showing that miR-27a can function as an oncogene by targeting MAP2K4 in the osteosarcoma MG63 cell line. 24556602 2014
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma
0.030 Biomarker disease BEFREE Overexpression of these genes was significantly associated to a poor response to treatment (P = .0001 and P = .0049, respectively), tumor progression, and worse overall survival (P = .0052 and P = .0085, respectively), suggesting that MAPK7 and MAP2K4 could play an important role in osteosarcoma tumorigenesis. 22154052 2012
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma
0.030 Biomarker disease LHGDN Increased radiation-induced apoptosis of Saos2 cells via inhibition of NFkappaB: a role for c-Jun N-terminal kinase. 16167336 2005