DisGeNET - a database of gene-disease associations

MAP2K4, mitogen-activated protein kinase kinase 4, 6416

N. diseases: 100; N. variants: 4

Disease: Pancreatic Neoplasm ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0030297
Disease:	Pancreatic Neoplasm

Pancreatic Neoplasm

0.310

Biomarker

disease

BEFREE

These results argue that MKK4 functions as a pro-oncogenic molecule instead of a suppressor in breast and pancreatic tumors.

2004

CUI:	C0030297
Disease:	Pancreatic Neoplasm

Pancreatic Neoplasm

0.310

CausalMutation

disease

CGI

CUI:	C0030297
Disease:	Pancreatic Neoplasm

Pancreatic Neoplasm

0.310

GenomicAlterations

disease

CGI