DisGeNET - a database of gene-disease associations

MAP2K4, mitogen-activated protein kinase kinase 4, 6416

N. diseases: 100; N. variants: 4

Disease: Ovarian Serous Adenocarcinoma ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C1335177
Disease:	Ovarian Serous Adenocarcinoma

Ovarian Serous Adenocarcinoma

0.310

AlteredExpression

disease

BEFREE

These findings suggest that homozygous deletion or reduced expression of MKK4 may contribute to the development of ovarian serous carcinoma.

16627982

2006

CUI:	C1335177
Disease:	Ovarian Serous Adenocarcinoma

Ovarian Serous Adenocarcinoma

0.310

GeneticVariation

disease

UNIPROT