BMP3, bone morphogenetic protein 3, 651

N. diseases: 32; N. variants: 2
Disease: Myopia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027092
Disease: Myopia
Myopia 		0.120 GeneticVariation disease GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
CUI: C0027092
Disease: Myopia
Myopia 		0.120 GeneticVariation disease BEFREE Two recent large-scale genome-wide association studies identified significant associations between myopia and single nucleotide polymorphisms (SNPs) near the PRSS56, BMP3, KCNQ5, LAMA2, TOX, TJP2, RDH5, ZIC2, RASGRF1, GJD2, RBFOX1, and SHISA6 genes. 25587058 2015
CUI: C0027092
Disease: Myopia
Myopia 		0.120 Biomarker disease BEFREE Our comparison with two previous studies suggested that BMP3 SNPs cause myopia primarily in Caucasian populations, while they may exhibit protective effects in Asian populations. 25335978 2014