SLC6A2, solute carrier family 6 member 2, 6530

N. diseases: 238; N. variants: 24
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 AlteredExpression group BEFREE Then histone acetyltransferase (HAT), histone deacetylase (HDAC), H3K27ac, NET, TNF-α, and interleukin-6 (IL-6) were detected by western blot in nine female subjects in different depression and hypertension groups, and Chromatin immunoprecipitation-polymerase chain reaction (Chip-PCR) were used to confirm the degree of acetylation affecting on the transcription level of NET gene. 30957546 2020
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 GeneticVariation group BEFREE Our study indicates that DNA methylation levels of nine CpG sites in NET gene promoter region are not associated with depression and hypertension. 28737436 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 Biomarker group BEFREE Plasma and lung tissues of patients with pulmonary hypertension were analyzed for NET markers. 27470511 2016
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 Biomarker group BEFREE The development of hypertension in preeclamptic women is also associated with endothelial dysfunction, which may be mediated by various mechanisms, including neutrophil activation and NET formation. 23633414 2013
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 Biomarker group CTD_human Effect of the rs168924 single-nucleotide polymorphism in the SLC6A2 catecholamine transporter gene on blood pressure in Caucasians. 22533655 2012
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 GeneticVariation group BEFREE A silent G1287A nucleotide substitution in exon 9 of the NET gene was studied in human conditions involving hypertension. 17124432 2006
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 Biomarker group LHGDN SLC6A2 may be one of the genes that contribute to hypertension in Japanese. 14620922 2003
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 Biomarker group BEFREE SLC6A2 may be one of the genes that contribute to hypertension in Japanese. 14620922 2003