Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
5-HTTLPR and <i>MTHFR 677C</i>>T polymorphisms and response to yoga-based lifestyle intervention in major depressive disorder: A randomized active-controlled trial.
|
30581206 |
2020 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Rare variants in SLC6A4 cause susceptibility to major depressive disorder with suicidal ideation in Han Chinese adolescents and young adults.
|
31629822 |
2020 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression.
|
31721892 |
2019 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Epigenetic variation at the SLC6A4 gene promoter in mother-child pairs with major depressive disorder.
|
30447571 |
2019 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Association between 5-HTTLPR polymorphism, suicide attempt and comorbidity in Mexican adolescents with major depressive disorder.
|
30724325 |
2019 |
Unipolar Depression
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Improvement in depressive symptoms (HDRS score declined) and increasing in 5-HTT mRNA level were found with longer duration of antidepressant treatment in patients with major depression.
|
29957477 |
2018 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The effects of 5-HTTLPR and BDNF Val66Met polymorphisms on neurostructural changes in major depressive disorder.
|
29414128 |
2018 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The 5-HTTLPR and BDNF polymorphisms moderate the association between uncinate fasciculus connectivity and antidepressants treatment response in major depression.
|
27277475 |
2017 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Voxel-based morphometric brain comparison between healthy subjects and major depressive disorder patients in Japanese with the s/s genotype of 5-HTTLPR.
|
28638109 |
2017 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The current study is a preliminary investigation of the association of polymorphisms of the serotonin transporter (SLC6A4), dopamine transporter (DAT1), dopamine receptor D4 (DRD4), and catechol-O-methyl transferase (COMT) genes with theory of mind decoding in a sample of adults with major depression.
|
26974654 |
2016 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Effects of polymorphisms of serotonin transporter promoter (5-HTTLPR) and brain derived neurotrophic factor gene (G196A rs6265) on the risk of major depressive disorder in the Chinese Han population.
|
27212180 |
2016 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In medication-free patients with current major depressive disorder (MDD; N=21), we determined 5-HTTLPR genotype, employed functional magnetic resonance imaging (fMRI) to examine amygdala responses to negative emotional stimuli, and used positron emission tomography with [(11)C]DASB to examine 5-HTT binding.
|
26561939 |
2016 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Amygdala responses to quetiapine XR and citalopram treatment in major depression: the role of 5-HTTLPR-S/Lg polymorphisms.
|
26879101 |
2016 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Carrying a genetic variant in the serotonin transporter gene (5HTT) may increase the risk of major depressive disorder and alcohol dependence.
|
26979101 |
2016 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We conducted an 8-week, open-label, prospective pilot study in 35 patients with major depressive disorder to assess the effects of genetic variations in SLC6A2 and SLC6A4 on both efficacy and side effect profile of desvenlafaxine.
|
27023264 |
2016 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our study included 2679 participants.Those with both the 5-HTTLPR s allele and the BDNF Met allele showed the highest risk of MD if they had previously experienced emotional (z = 2.08, p = 0.037), sexual (z = 2.19, p = 0.029) or any kind of childhood abuse (z = 2.37, p = 0.018).
|
25510949 |
2015 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.
|
25650523 |
2015 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Our study included 2679 participants.Those with both the 5-HTTLPR s allele and the BDNF Met allele showed the highest risk of MD if they had previously experienced emotional (z = 2.08, p = 0.037), sexual (z = 2.19, p = 0.029) or any kind of childhood abuse (z = 2.37, p = 0.018).
|
25510949 |
2015 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Association of serotonin transporter (SLC6A4) and receptor (5HTR1A, 5HTR2A) polymorphisms with response to treatment with escitalopram in patients with major depressive disorder: A preliminary study.
|
26261165 |
2015 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Results show that 5-HTTLPR is strongly associated with the major depressive disorder in postpartum women.
|
24882202 |
2014 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirtazapine in patients with major depressive disorder.
|
24911443 |
2014 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response.
|
24679990 |
2014 |
Unipolar Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: insights in depression.
|
24972302 |
2014 |
Unipolar Depression
|
0.600 |
PosttranslationalModification
|
disease |
BEFREE |
The potential of SLC6A4 gene methylation analysis for the diagnosis and treatment of major depression.
|
24657235 |
2014 |
Unipolar Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The influence of 5-HTTLPR genotype on the association between the plasma concentration and therapeutic effect of paroxetine in patients with major depressive disorder.
|
24858363 |
2014 |