SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 440; N. variants: 28
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.510 Biomarker disease CTD_human Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls. 17000009 2006
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.510 Biomarker disease PSYGENET To study the impact of genetic factors that play an important role in an individual's vulnerability to alcohol abuse and dependence, we examined the genetic variations of the major neurotransmitter genes, including the dopamine D2 receptor (DRD2) TaqI A, B, and -141C insertion/deletion (Ins/Del) polymorphisms, the serotonin transporter-linked polymorphic region (5-HTTLPR), and the gamma-aminobutyric acid A (GABA(A)) receptor beta(3) subunit gene (GABRbeta3), for 130 Mexican-American alcoholic men and 251 nonalcoholic control subjects (105 men and 146 women). 15066703 2004
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.510 Biomarker disease CTD_human Interaction between serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates. 15520362 2004
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.510 GeneticVariation disease BEFREE To study the impact of genetic factors that play an important role in an individual's vulnerability to alcohol abuse and dependence, we examined the genetic variations of the major neurotransmitter genes, including the dopamine D2 receptor (DRD2) TaqI A, B, and -141C insertion/deletion (Ins/Del) polymorphisms, the serotonin transporter-linked polymorphic region (5-HTTLPR), and the gamma-aminobutyric acid A (GABA(A)) receptor beta(3) subunit gene (GABRbeta3), for 130 Mexican-American alcoholic men and 251 nonalcoholic control subjects (105 men and 146 women). 15066703 2004
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.510 Biomarker disease PSYGENET Polymorphism of the serotonin transporter: implications for the use of selective serotonin reuptake inhibitors. 12083964 2001