Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 AlteredExpression disease BEFREE SWI/SNF protein expression status in fumarate hydratase-deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients. 29689242 2018
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 Biomarker disease BEFREE Additionally, in about 40% of ccRCC cases the mutation in <i>PBRM1</i> (<i>POLYBROMO1</i>) gene coding for a non-core subunit of SWI/SNF chromatin remodeling complex was found suggesting potential impairment of this complex function in ccRCC. 29218250 2017
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 GeneticVariation disease BEFREE PBRM1 encodes for BAF180, a component of the SWI/SNF chromatin remodeling complex, and is inactivated in, on average, 36% of clear cell renal cell carcinoma (ccRCC). 26166446 2015
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 Biomarker disease BEFREE The role of SWI/SNF complex in rhabdoid RCC should be further studied on a larger number of cases. 24817979 2014
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 Biomarker disease BEFREE Polybromo-1 (PBRM1), a SWI/SNF complex subunit is a prognostic marker in clear cell renal cell carcinoma. 24053427 2014
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 GeneticVariation disease BEFREE Recently, exome sequencing studies have revealed that the SWI/SNF (switch/sucrose nonfermentable) members PBRM1 and ARID1A are mutated in ccRCC, and it has also been suggested that aberrant chromatin regulation is a key step in kidney cancer pathogenesis. 23416164 2013