Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.400 Biomarker disease BEFREE Subgroup analysis showed that T2DM was negatively associated with ALS in patients whose age at the first T2DM diagnosis was ≥ 55 years. 31152300 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.400 GeneticVariation disease BEFREE Interactions between plasma copper concentrations and SOD1 gene polymorphism for impaired glucose regulation and type 2 diabetes. 30909159 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.400 AlteredExpression disease BEFREE Altered superoxide dismutase-1 activity and intercellular adhesion molecule 1 (ICAM-1) levels in patients with type 2 diabetes mellitus. 31042755 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.400 Biomarker disease BEFREE Serum Extracellular Superoxide Dismutase Is Associated with Diabetic Retinopathy Stage in Chinese Patients with Type 2 Diabetes Mellitus. 29849828 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.400 Biomarker disease BEFREE Metformin enhanced SOD and GPx activities in type 2 diabetes patients but the reflection of this increase to the total antioxidant capacity was not significant. 30098371 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.400 AlteredExpression disease BEFREE The SOD (14.139 ± 1.479 U/mgprot) and GSH-PX (81.511 ± 5.276 U/mgprot) levels significantly decreased in NAFLD with T2DM rats, while the levels of these indicators increased after treatment with TGJ. 30460863 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.400 GeneticVariation disease BEFREE Influence of arterial hypertension, type 2 diabetes and cardiovascular risk factors on ALS outcome: a population-based study. 28616937 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.400 GeneticVariation disease BEFREE Genetic polymorphisms (Pro197Leu of Gpx1, +35A/C of SOD1, -262C/T of CAT), the level of antioxidant proteins (GPx1, SOD1, CAT) and the risk of distal symmetric polyneuropathy in Polish patients with type 2 diabetes mellitus. 26674569 2016
Diabetes Mellitus, Non-Insulin-Dependent
0.400 GeneticVariation disease BEFREE Association of Superoxide dismutases (SOD1 and SOD2) and Glutathione peroxidase 1 (GPx1) gene polymorphisms with type 2 diabetes mellitus. 25283363 2015
Diabetes Mellitus, Non-Insulin-Dependent
0.400 GeneticVariation disease BEFREE We investigated associations of allelic variations in SOD1 gene with nephropathy and cardiovascular complications in patients with type 2 diabetes. 22608880 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.400 AlteredExpression disease BEFREE The offspring of T2D patients had increased levels of serum ferritin (P < 0.01) and lower transferrin receptor (P < 0.008); higher insulin (P < 0.03) and total and LDL cholesterol; higher heme oxygenase and SOD activities increased TBARS and lower GSH; decreased mitofusin and Bcl/Bax expression ratios compared to offspring of normal subjects. 22450556 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.400 GeneticVariation disease BEFREE Genetic variants C1167T of CAT gene and +35 A/C of SOD1 gene has no role in insulin resistance in T2DM. 22970972 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.400 Biomarker disease CTD_human Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin. 15531508 2004
Diabetes Mellitus, Non-Insulin-Dependent
0.400 Biomarker disease BEFREE The association between the polymorphisms of three different antioxidative enzyme - catalase, copper-zinc superoxide dismutase (Cu/ Zn-SOD) and extracellular superoxide dismutase (EC-SOD) - genes and macroangiopathy was examined in patients with type 2 diabetes mellitus. 11350569 2001