SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Disease: Kidney Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.340 GeneticVariation group BEFREE In this review, I briefly discussed the role of OPN and its gene polymorphisms in kidney physiology, as well as in various kidney diseases. 30456594 2019
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.340 Biomarker group BEFREE To characterize further the role of OPN in kidney injury we used OPN<sup>-/-</sup> mice in antiglomerular basement membrane reactive serum-induced immune (NTS) nephritis, an inflammatory and progressive model of kidney disease. 29717936 2018
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.340 AlteredExpression group BEFREE Meta-analysis revealed that, compared with the control group, the OPN level was significantly higher in the SLE group (SMD = 0.965, 95% CI = 0.337-1.393, p = 0.001) and in the SLE group with renal disease (SMD = 2.219, 95% CI = 0.681-3.757, p = 0.005). 27307447 2017
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.340 Biomarker group CTD_human Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury. 27026710 2016
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.340 Biomarker group BEFREE Osteopontin (OPN) has been suggested to be associated with renal diseases characterized by tubulointerstitial fibrosis and proteinuria. 22584029 2012