SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.030 AlteredExpression disease BEFREE Immunocytochemistry of bone marrow biopsies of AML patients confirmed the positive expression of osteopontin in blasts near the para-trabecular bone marrow, whereas osteopontin was rarely detected in mononuclear cell isolates. 29340063 2017
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.030 GeneticVariation disease BEFREE The OPN gene polymorphism confers the susceptibility and response to Ara-C based chemotherapy in Chinese AML patients. 25591760 2015
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.030 Biomarker disease BEFREE Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. 19805619 2009